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  1. Content type: Research article

    The purpose of this study was to investigate the frequency and the distribution of inflammatory cell infiltrate in two sets of cutaneous biopsies derived from clinically affected and unaffected skin in patient...

    Authors: Silvia Bosello, Cristiana Angelucci, Gina Lama, Stefano Alivernini, Gabriella Proietti, Barbara Tolusso, Gigliola Sica, Elisa Gremese and Gianfranco Ferraccioli

    Citation: Arthritis Research & Therapy 2018 20:75

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  2. Content type: Research article

    Osteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and ...

    Authors: Portia P. E. Flowers, Rebecca J. Cleveland, Todd A. Schwartz, Amanda E. Nelson, Virginia B. Kraus, Howard J. Hillstrom, Adam P. Goode, Marian T. Hannan, Jordan B. Renner, Joanne M. Jordan and Yvonne M. Golightly

    Citation: Arthritis Research & Therapy 2018 20:76

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  3. Content type: Research article

    Knee pain is common with obesity and weight gain being important risk factors. Previous clinical trials have focused on overweight or obese adults with knee pain and osteoarthritis and demonstrated modest effe...

    Authors: Yuanyuan Wang, Catherine Lombard, Sultana Monira Hussain, Cheryce Harrison, Samantha Kozica, Sharmayne R. E. Brady, Helena Teede and Flavia M. Cicuttini

    Citation: Arthritis Research & Therapy 2018 20:74

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  4. Content type: Research article

    Premature atherosclerosis is one of the major complications of systemic lupus erythematosus (SLE). Recently, the biological linkage between atherosclerosis and osteoporosis has garnered much attention. The aim...

    Authors: Kazumasa Ohmura, Masaru Kato, Toshiyuki Watanabe, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Shinsuke Yasuda, Yoichi M. Ito, Norihiro Sato and Tatsuya Atsumi

    Citation: Arthritis Research & Therapy 2018 20:72

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  5. Content type: Research article

    The efficacy of corticosteroids in patients with psoriatic arthritis (PsA) and inflammatory back pain has not been studied to date. In this controlled trial, we aimed to investigate the comparative performance...

    Authors: Muhammad Haroon, Muddassar Ahmad, Muhammad Nouman Baig, Olivia Mason, John Rice and Oliver FitzGerald

    Citation: Arthritis Research & Therapy 2018 20:73

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  6. Content type: Correction

    After publication of the article [1], it has been brought to our attention that the labels in Fig. 2b have been switched and are as a result incorrect. The label for the red line should have the label “non-CAM...

    Authors: Hanbo Yang, Qinglin Peng, Liguo Yin, Shanshan Li, Jingli Shi, Yamei Zhang, Xin Lu, Xiaoming Shu, Sigong Zhang and Guochun Wang

    Citation: Arthritis Research & Therapy 2018 20:71

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    The original article was published in Arthritis Research & Therapy 2017 19:259

  7. Content type: Research article

    The aim of this study was to assess the outcomes of remission induction in patients with IgG4-related disease (IgG4-RD) in our cohort, and to investigate the characteristics, prognosis, and risk factors in the...

    Authors: Liwen Wang, Panpan Zhang, Mu Wang, Ruie Feng, Yamin Lai, Linyi Peng, Yunyun Fei, Xuan Zhang, Yan Zhao, Xiaofeng Zeng, Fengchun Zhang and Wen Zhang

    Citation: Arthritis Research & Therapy 2018 20:65

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  8. Content type: Research article

    Osteoclasts have been strongly implicated in osteoarthritic cartilage degradation, at least indirectly via bone resorption, and have been shown to degrade cartilage in vitro. The osteoclast resorption processe...

    Authors: Henrik Löfvall, Hannah Newbould, Morten A. Karsdal, Morten H. Dziegiel, Johan Richter, Kim Henriksen and Christian S. Thudium

    Citation: Arthritis Research & Therapy 2018 20:67

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  9. Content type: Research article

    African Americans with systemic lupus erythematosus (SLE) have increased renal disease compared to Caucasians, but differences in other comorbidities have not been well-described. We used an electronic health ...

    Authors: April Barnado, Robert J. Carroll, Carolyn Casey, Lee Wheless, Joshua C. Denny and Leslie J. Crofford

    Citation: Arthritis Research & Therapy 2018 20:69

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  10. Content type: Research article

    Tripterygium wilfordii Hook F (TwHF) alone or in combination with methotrexate (MTX) has been shown to be more effective than MTX monotherapy in controlling the manifestations in subjects with disease-modifying a...

    Authors: Yang-zhong Zhou, Li-dan Zhao, Hua Chen, Yan Zhang, Dan-feng Wang, Lin-fang Huang, Qian-wen Lv, Bin Liu, Zhenbin Li, Wei Wei, Hongbin Li, Xiangping Liao, Hui Liu, Xiumei Liu, Hongtao Jin, Junxiang Wang…

    Citation: Arthritis Research & Therapy 2018 20:70

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  11. Content type: Research article

    Innate immunity including macrophages (Mϕ) in lupus nephritis (LN) has been gaining attention, but roles of Mϕ in LN remain uncertain.

    Authors: Daiga Kishimoto, Yohei Kirino, Maasa Tamura, Mitsuhiro Takeno, Yosuke Kunishita, Kaoru Takase-Minegishi, Hiroto Nakano, Ikuma Kato, Kiyotaka Nagahama, Ryusuke Yoshimi, Kazuhiko Igarashi, Ichiro Aoki and Hideaki Nakajima

    Citation: Arthritis Research & Therapy 2018 20:64

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  12. Content type: Research article

    Anticitrullinated protein antibodies (ACPA) and citrullinated proteins play key roles in the pathogenesis of rheumatoid arthritis (RA). Many candidate citrullinated antigens have been identified in joints, but...

    Authors: Hoshimi Kawaguchi, Isao Matsumoto, Atsumu Osada, Izumi Kurata, Hiroshi Ebe, Yuki Tanaka, Asuka Inoue, Naoto Umeda, Yuya Kondo, Hiroto Tsuboi, Yasuhiro Shinkai, Yoshito Kumagai, Akihito Ishigami and Takayuki Sumida

    Citation: Arthritis Research & Therapy 2018 20:66

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  13. Content type: Letter

    Authors: Giovanni Orsolini, Ombretta Viapiana, Maurizio Rossini, Giovanni Adami, Cristian Caimmi, Angelo Fassio and Davide Gatti

    Citation: Arthritis Research & Therapy 2018 20:63

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    The original article was published in Arthritis Research & Therapy 2018 20:16

  14. Content type: Research article

    Although infrequent, some rheumatoid arthritis (RA) patients achieve disease-modifying antirheumatic drug (DMARD)-free sustained remission. The absence of RA-specific autoantibodies, such as anticitrullinated ...

    Authors: L. E. Burgers, D. M. Boeters, M. Reijnierse and A. H. M. van der Helm-van Mil

    Citation: Arthritis Research & Therapy 2018 20:68

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  15. Content type: Research article

    Granulocyte macrophage-colony stimulating factor (GM-CSF) has been implicated in the pathogenesis of a number of inflammatory diseases and in osteoarthritis (OA). We identified previously a new GM-CSF→Jmjd3→in...

    Authors: Ming-Chin Lee, Reem Saleh, Adrian Achuthan, Andrew J. Fleetwood, Irmgard Förster, John A. Hamilton and Andrew D. Cook

    Citation: Arthritis Research & Therapy 2018 20:62

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  16. Content type: Research article

    Adalimumab was effective in treating patients with nonradiographic axial spondyloarthritis (nr-axSpA) in the 12-week ABILITY-1 trial. We present long-term efficacy and safety results of adalimumab from the ope...

    Authors: Désirée van der Heijde, Joachim Sieper, Walter P. Maksymowych, Robert G. Lambert, Su Chen, Maja Hojnik, Jaclyn K. Anderson and Aileen L. Pangan

    Citation: Arthritis Research & Therapy 2018 20:61

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  17. Content type: Research article

    The aim was to assess patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA) treated with filgotinib during two phase 2b, 24-week, randomized, placebo-controlled studies.

    Authors: Mark Genovese, Rene Westhovens, Luc Meuleners, Annegret Van der Aa, Pille Harrison, Chantal Tasset and Arthur Kavanaugh

    Citation: Arthritis Research & Therapy 2018 20:57

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  18. Content type: Research article

    Tofacitinib is the first oral Janus kinase inhibitor approved for the treatment of rheumatoid arthritis (RA). We compared the effectiveness and safety of tofacitinib, disease-modifying antirheumatic drugs (DMA...

    Authors: Marina Amaral de Ávila Machado, Cristiano Soares de Moura, Steve Ferreira Guerra, Jeffrey R. Curtis, Michal Abrahamowicz and Sasha Bernatsky

    Citation: Arthritis Research & Therapy 2018 20:60

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  19. Content type: Research article

    Defining environmental factors responsible for development of autoimmunity in rheumatoid arthritis (RA) is critical for understanding mechanisms of disease initiation and propagation. Notably, a history of cig...

    Authors: Laura C. Cappelli, Maximilian F. Konig, Allan C. Gelber, Clifton O. Bingham III and Erika Darrah

    Citation: Arthritis Research & Therapy 2018 20:59

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  20. Content type: Commentary

    Europe and North America have been leaders in rheumatology for many years. However, for more than a decade now the East Asian region has been catching up dramatically. Some aspects of rheumatology in East Asia...

    Authors: Kazuhiko Yamamoto, Yeong-Wook Song and Zhan-guo Li

    Citation: Arthritis Research & Therapy 2018 20:58

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  21. Content type: Research article

    Effects of methotrexate (MTX) on the proliferation of rheumatoid arthritis (RA) synovial fibroblasts are incompletely understood. We explored actions of MTX in view of circadian transcriptions of synovial fibr...

    Authors: Kohjin Suzuki, Kohsuke Yoshida, Takeshi Ueha, Kenta Kaneshiro, Ayako Nakai, Naonori Hashimoto, Koto Uchida, Teppei Hashimoto, Yoshiko Kawasaki, Nao Shibanuma, Natsuko Nakagawa, Yoshitada Sakai and Akira Hashiramoto

    Citation: Arthritis Research & Therapy 2018 20:55

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  22. Content type: Research article

    The chemokine receptors CXCR3 and CXCR4 are involved in the pathogenesis of fibrosis, a key feature of systemic sclerosis (SSc). It is hypothesized that immunoglobulin (Ig)G antibodies (abs) against these two ...

    Authors: Florian Weigold, Jeannine Günther, Moritz Pfeiffenberger, Otavio Cabral-Marques, Elise Siegert, Duska Dragun, Aurélie Philippe, Ann-Katrin Regensburger, Andreas Recke, Xinhua Yu, Frank Petersen, Rusan Catar, Robert Biesen, Falk Hiepe, Gerd R. Burmester, Harald Heidecke…

    Citation: Arthritis Research & Therapy 2018 20:52

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  23. Content type: Research article

    Diuretics have been associated with impaired response and refractoriness in gout, but whether this effect is still present with new urate-lowering drugs (ULD) and treat-to-target strategies is unknown. The aim...

    Authors: Laura Ranieri, Carolina Contero, Maria-Luisa Peral, Irene Calabuig, Pedro Zapater and Mariano Andres

    Citation: Arthritis Research & Therapy 2018 20:53

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  24. Content type: Research article

    Published methods for quantification of magnetic resonance imaging (MRI) evidence of inflammation in the sacroiliac joint lack validation in pediatric populations. We evaluated the reliability and construct va...

    Authors: Pamela F. Weiss, Walter P. Maksymowych, Robert G. Lambert, Jacob L. Jaremko, David M. Biko, Joel Paschke, Timothy G. Brandon, Rui Xiao and Nancy A. Chauvin

    Citation: Arthritis Research & Therapy 2018 20:56

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