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  1. Content type: Research article

    The phase III MONARCH randomized controlled trial (NCT02332590) demonstrated that in patients with rheumatoid arthritis (RA), sarilumab (anti-interleukin-6 receptor monoclonal antibody) monotherapy is superior...

    Authors: Vibeke Strand, Laure Gossec, Clare W. J. Proudfoot, Chieh-I Chen, Matthew Reaney, Sophie Guillonneau, Toshio Kimura, Janet van Adelsberg, Yong Lin, Erin K. Mangan, Hubert van Hoogstraten and Gerd R. Burmester

    Citation: Arthritis Research & Therapy 2018 20:129

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  2. Content type: Research article

    In this study, we evaluated whether platelet-rich plasma (PRP) is superior to hyaluronic acid (HA) in the treatment of knee osteoarthritis.

    Authors: Yalong Di, Changxu Han, Liang Zhao and Yizhong Ren

    Citation: Arthritis Research & Therapy 2018 20:128

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  3. Content type: Research article

    Previous studies have revealed that hepatitis B virus (HBV) infection may be related to rheumatoid arthritis (RA), but there are no studies on the presence of HBV antigens or nucleic acid in synovium from pati...

    Authors: Yu-Lan Chen, Jun Jing, Ying-Qian Mo, Jian-Da Ma, Li-Juan Yang, Le-Feng Chen, Xiang Zhang, Tao Yan, Dong-Hui Zheng, Frank Pessler and Lie Dai

    Citation: Arthritis Research & Therapy 2018 20:130

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  4. Content type: Research article

    Rheumatoid arthritis (RA) is a chronic inflammatory disease in which adults have significant joint issues leading to poor health. Poor health is compounded by many factors, including exercise avoidance and inc...

    Authors: David B. Bartlett, Leslie H. Willis, Cris A. Slentz, Andrew Hoselton, Leslie Kelly, Janet L. Huebner, Virginia B. Kraus, Jennifer Moss, Michael J. Muehlbauer, Guillaume Spielmann, William E. Kraus, Janet M. Lord and Kim M. Huffman

    Citation: Arthritis Research & Therapy 2018 20:127

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  5. Content type: Research article

    The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to id...

    Authors: Fulvia Ceccarelli, Carlo Perricone, Tania Colasanti, Laura Massaro, Enrica Cipriano, Monica Pendolino, Francesco Natalucci, Riccardo Mancini, Francesca Romana Spinelli, Guido Valesini, Fabrizio Conti and Cristiano Alessandri

    Citation: Arthritis Research & Therapy 2018 20:126

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  6. Content type: Correction

    Unfortunately, after publication of this article [1], it was noticed that the panel for Fig. 4b was inadvertently obscured during the production process. The full, correct Fig. 4 can be seen below and the orig...

    Authors: Jie Qian, Lingxiao Xu, Xiaoxuan Sun, Yani Wang, Wenhua Xuan, Qian Zhang, Pengfei Zhao, Qin Wu, Rui Liu, Nan Che, Fang Wang, Wenfeng Tan and Miaojia Zhang

    Citation: Arthritis Research & Therapy 2018 20:125

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    The original article was published in Arthritis Research & Therapy 2018 20:26

  7. Content type: Research article

    Low C-C chemokine receptor 1 (CCR1) and interleukin (IL)-10 expression is associated with risk of Behçet’s disease (BD). The objective of the present study was to clarify the pathological roles of CCR1 and IL10 l...

    Authors: Hiroto Nakano, Yohei Kirino, Mitsuhiro Takeno, Kana Higashitani, Hideto Nagai, Ryusuke Yoshimi, Yukie Yamaguchi, Ikuma Kato, Ichiro Aoki and Hideaki Nakajima

    Citation: Arthritis Research & Therapy 2018 20:124

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  8. Content type: Research article

    Epidemiologic studies have highlighted the association of environmental factors with the development and progression of autoimmune and chronic inflammatory diseases. Among the environmental factors, smoking ha...

    Authors: Jhimmy Talbot, Raphael S. Peres, Larissa G. Pinto, Rene D. R. Oliveira, Kalil A. Lima, Paula B. Donate, Jaqueline R. Silva, Bernard Ryffel, Thiago M. Cunha, José C. Alves-Filho, Foo Y. Liew, Paulo Louzada-Junior and Fernando de Queiroz Cunha

    Citation: Arthritis Research & Therapy 2018 20:119

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  9. Content type: Research article

    Systemic lupus erythematosus (SLE) is a chronic and incurable autoimmune disease involving the dysfunction of lymphocytes. Circular RNAs (circRNAs) are noncoding RNAs (ncRNAs) with a covalently closed loop str...

    Authors: Xin Wang, Chengzhong Zhang, Zhouwei Wu, Yue Chen and Weimin Shi

    Citation: Arthritis Research & Therapy 2018 20:118

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  10. Content type: Research article

    The pathogenesis of sacroiliitis is unclear; therefore, we aimed to systematically study the immunopathology of sacroiliitis in patients with axial spondyloarthritis (axSpA), and explore the relationship betwe...

    Authors: Dan min Wang, Ling Lin, Jian hua Peng, Yao Gong, Zhi duo Hou, Su biao Chen and Zheng yu Xiao

    Citation: Arthritis Research & Therapy 2018 20:120

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  11. Content type: Review

    Approaches for the prevention and treatment of hip osteoarthritis (OA) remain limited. There are recent data suggesting that low birth weight (LBW) and preterm birth may be risk factors for hip osteoarthritis....

    Authors: Sultana Monira Hussain, Ilana N. Ackerman, Yuanyuan Wang, Ella Zomer and Flavia M. Cicuttini

    Citation: Arthritis Research & Therapy 2018 20:121

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  12. Content type: Research article

    Rheumatoid arthritis (RA) patients are at high risk of developing cardiovascular disease (CVD). In RA, chronic inflammation may lead to endothelial dysfunction, an early indicator of CVD, owing to diminished n...

    Authors: Unnikrishnan M. Chandrasekharan, Zeneng Wang, Yuping Wu, W. H. Wilson Tang, Stanley L. Hazen, Sihe Wang and M. Elaine Husni

    Citation: Arthritis Research & Therapy 2018 20:123

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  13. Content type: Letter

    Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis (ROC), registered 22 October 2009, NCT01000441

    Authors: Elodie Rivière, Jérémie Sellam, Juliette Pascaud, Philippe Ravaud, Jacques-Eric Gottenberg and Xavier Mariette

    Citation: Arthritis Research & Therapy 2018 20:122

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  14. Content type: Research article

    The prevalence of dermatomyositis (DM) versus DM and polymyositis (PM) combined has been shown to be negatively associated with latitude. This observation has been attributed to increasing exposure to ultravio...

    Authors: Joanna E. Parkes, Simon Rothwell, Alexander Oldroyd, Hector Chinoy and Janine A. Lamb

    Citation: Arthritis Research & Therapy 2018 20:117

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  15. Content type: Research article

    IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony anky...

    Authors: Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae and Tae-Hwan Kim

    Citation: Arthritis Research & Therapy 2018 20:115

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  16. Content type: Research article

    B cells exert their pathogenic action in rheumatoid arthritis (RA) locally in the synovium. This study was undertaken to elucidate the chemokines responsible for the recruitment of B cells in the inflamed syno...

    Authors: Estefanía Armas-González, María Jesús Domínguez-Luis, Ana Díaz-Martín, Mayte Arce-Franco, Javier Castro-Hernández, Gabriela Danelon, Vanesa Hernández-Hernández, Sagrario Bustabad-Reyes, Alberto Cantabrana, Mariagrazia Uguccioni and Federico Díaz-González

    Citation: Arthritis Research & Therapy 2018 20:114

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  17. Content type: Research article

    Pain is one of the most important domains affecting health-related quality of life (HRQoL) in patients with psoriatic arthritis (PsA). Secukinumab has demonstrated rapid and sustained improvements in signs and...

    Authors: Iain B. McInnes, Philip J. Mease, Georg Schett, Bruce Kirkham, Vibeke Strand, Nicole Williams, Todd Fox, Luminita Pricop, Steffen M. Jugl and Kunal K. Gandhi

    Citation: Arthritis Research & Therapy 2018 20:113

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  18. Content type: Research article

    There is growing evidence that mast cells (MCs) play a role in knee osteoarthritis (OA). H1-antihistamines block H1-receptors of histamine, which is an important mediator of MCs. There is a lack of data on whethe...

    Authors: Ivan Shirinsky and Valery Shirinsky

    Citation: Arthritis Research & Therapy 2018 20:116

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  19. Content type: Research article

    Gout is a metabolic disease and is the most common form of inflammatory arthritis affecting men. However, the pathogenesis of gout is still uncertain, and novel biomarkers are needed for early prediction and d...

    Authors: Yannan Zhang, Huanzhen Zhang, Dong Chang, Fuchuan Guo, Hongzhi Pan and Yuexin Yang

    Citation: Arthritis Research & Therapy 2018 20:111

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  20. Content type: Research article

    Aerobic exercise in general and high-intensity interval training (HIIT) specifically is known to improve vascular function in a range of clinical conditions. HIIT in particular has demonstrated improvements in...

    Authors: A. Mitropoulos, A. Gumber, H. Crank, M. Akil and M. Klonizakis

    Citation: Arthritis Research & Therapy 2018 20:112

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  21. Content type: Research article

    Prior qualitative research on gout has focused primarily on barriers to disease management. Our objective was to use patients’ perspectives to construct an explanatory framework to understand how patients beco...

    Authors: Alyssa Howren, Susan M. Cox, Kam Shojania, Sharan K. Rai, Hyon K. Choi and Mary A. De Vera

    Citation: Arthritis Research & Therapy 2018 20:110

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  22. Content type: Research article

    The aim of this study is to examine the occurrence of comorbidities at the time of first diagnosis of gout compared with matched population controls, overall and by sex, as well as to examine the crude and age...

    Authors: Panagiota Drivelegka, Valgerdur Sigurdardottir, Anna Svärd, Lennart T. H. Jacobsson and Mats Dehlin

    Citation: Arthritis Research & Therapy 2018 20:108

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  23. Content type: Research article

    The relationship between inflammation and blood pressure (BP) has been studied mainly in the general population. In this study, we examined the association between inflammation and BP across a broader range of...

    Authors: Zhi Yu, Seoyoung C. Kim, Kathleen Vanni, Jie Huang, Rishi Desai, Shawn N. Murphy, Daniel H. Solomon and Katherine P. Liao

    Citation: Arthritis Research & Therapy 2018 20:107

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  24. Content type: Research article

    The perceived bother of skin and joint-related manifestations of psoriatic disease may differ among patients, rheumatologists, and dermatologists. This study identified and compared the patient and dermatologi...

    Authors: M. Elaine Husni, Anthony Fernandez, Brett Hauber, Rakesh Singh, Joshua Posner, Jessie Sutphin and Arijit Ganguli

    Citation: Arthritis Research & Therapy 2018 20:102

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