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Figure 2 | Arthritis Res Ther

Figure 2

From: Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes

Figure 2

Effect of IL-1β, tumor necrosis factor alpha (TNF-α) and IL-17 used alone and in combination on C-Jun translocation. Rheumatoid arthritis synoviocytes were stimulated for 30 min with cytokines at the cited concentrations. Cells were fixed in 4% paraformadehyde and immunofluorescence staining was performed. Results are representative of three independent experiments. Effects of proinflammatory cytokines used alone at low and optimal concentrations and in combination on C-Jun nuclear translocation after 30 min of exposure are shown.

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