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Table 1 IFN-γ production by CD4+ T cells in lymph nodes and the spleen

From: Induction of IL-10-producing CD4+CD25+T cells in animal model of collagen-induced arthritis by oral administration of type II collagen

 

% IFN-γ-positive cells

Site

Without CII stimulation

With CII stimulation

Peyer's patch

  

   CIA

3.4 ± 0.22

26.6 ± 0.6

   Tolerized

4.6 ± 0.1

8.9 ± 0.2

Mesentric lymph node

  

   CIA

3.3 ± 0.4

34 ± 0.2

   Tolerized

2.3 ± 0.5

5.6 ± 0.8

Spleen

  

   CIA

5.4 ± 0.01

42.6± 0.1

   Tolerized

4.5 ± 0.2

5.3 ± 0.02

  1. Values are expressed as mean ± standard deviation, calculated from three independent measurements. CIA, collagen-induced arthritis; CII, type II collagen.
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Arthritis Research & Therapy

ISSN: 1478-6362

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