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Table 3 Expression of adhesion molecules

From: Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study

 

Baseline

Week 4

ICAM-1 skin

2539 ± 425

532 ± 81**

ICAM-1 synovial sublining

45382 ± 18097

10617 ± 3385*

VCAM-1 skin

12242 ± 1334

6916 ± 1386*

VCAM-1 synovium

4071 ± 1205

2419 ± 1052

E-selectin skin

625 ± 179

30 ± 8**

E-selectin synovium

731 ± 224

494 ± 344

  1. Expression of adhesion molecules in lesional skin and synovial biopsies (integrated optical density/mm2) before and 4 weeks after initiation of infliximab therapy. The data are expressed as mean ± standard error of the mean. ICAM, intercellular adhesion molecule; VCAM, vascular cell adhesion molecule. *P ≤ 0.05, **P ≤ 0.02, versus baseline.