Table 2 Differentially expressed autoimmune genes
From: Gene expression signatures for autoimmune disease in peripheral blood mononuclear cells
Category | Gene symbol |
Underexpressed in autoimmune | Â |
   Apoptosis | TRADD, TRAP1, TRIP, TRAF2, CASP6, CASP8, TP53, SIVA |
   Ubiquitin/proteasome | UBE2M, UBE2G2, POH1 |
   Cell cycle inhibitors | CDKN1B, CDKN2A, BRCA1 |
   Differentiation inducers | LIF, CD24 |
   Enzyme inhibitors | APOC3, KAL1 |
Overexpressed in autoimmune | Â |
   Receptors | CSF3R, HLA-DMB, HLALS, TGFBR2, BMPR2 |
   Inflammatory mediators | MSTP9, BDNF, CES1, CYR61 |
   Signaling/2nd messenger | FASTK, DGKA, DGKD |
   Autoantigens | GARS, GAD2 |