Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression

Table 1 DNA fragmentation in human rheumatoid arthritis fibroblast-like synoviocytes after diosgenin treatment

Apoptosis was quantified on floating and adherent cells using ELISA (see Materials and methods). The fold induction of DNA fragmentation is shown relative to the value for the control culture, which is taken as 1. Data are expressed as mean ± SD of three experiments from three different patients. *^,#A P value less than 0.05 (Fisher's protected-least-significant-difference test) was considered to indicate significance in comparison with controls.

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