Figure 1
From: A proinflammatory role for Fas in joints of mice with collagen-induced arthritis
The lpr phenotype is mild in the DBA/1J genetic background. Analysis of surface expression of CD4/CD8 (a, b), CD90/CD45 (c, d), and Fas (CD95) (e, f) on T lymphocytes purified from lymph nodes of 24-week-old DBA/1J-lpr/lpr mice (b, d, f) and DBA/1J littermates (a, c, e). Lymph node cells were stained with the indicated antibodies (Becton Dickinson). For analysis of CD95 (open area), an isotype control (shadowed area) is shown (e, f). Samples were analyzed on a FACScan cell sorter (Becton Dickinson).