Skip to main content

Table 1 Effect of enzymatic treatment on cell viability in cartilage wound edges 5 weeks after subcutaneous implantation in nude mice

From: Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model

Zone Unwounded Not enzyme treated Enzyme treated
Surface 1440 ± 175 1151 ± 133 2316 ± 209*
Middle 787 ± 160 866 ± 27 1097 ± 59*
Deep 646 ± 75 589 ± 16 960 ± 45*
  1. Cartilage was treated with hyaluronidase and collagenase or left untreated and implanted subcutaneously into nude mice for 5 weeks. The number of vital cells were counted in a 150-mm broad band along both sides of the wound edges, as well as in unwounded control areas in surface, middle and deep zones. *P < 0.05 versus unwounded areas and non-enzyme-treated wound areas.