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Table 1 Differential activation of MAPK/SAPK in the synovial subcompartments of RA

From: The stressed synovium

Signalling pathway Synovial-lining layer Sublining layer Mononuclear infiltrates Perivascular region Vascular endothelium
p38 +++ + + - +++
ERK - + - +++ -
JNK + ++ ++ + -