Table 1 Differential activation of MAPK/SAPK in the synovial subcompartments of RA
From: The stressed synovium
| Signalling pathway | Synovial-lining layer | Sublining layer | Mononuclear infiltrates | Perivascular region | Vascular endothelium |
|---|---|---|---|---|---|
| p38 | +++ | + | + | - | +++ |
| ERK | - | + | - | +++ | - |
| JNK | + | ++ | ++ | + | - |