Figure 1
From: The human exosome: an autoantigenic complex of exoribonucleases in myositis and scleroderma
Schematic representation of the human exosome complex. The associations between individual components of the human exosome are hypothetical, since no structural data have been presented to date. All human exosome components analyzed so far (PM/Scl-100, PM/Scl-75, hRrp4p, hRrp40p, hRrp41p, hRrp42p, hRrp46p, and hCsl4p) are recognized by autoantibodies present in IIM sera, although some (PM/Scl-100, PM/Scl-75, and hRrp4p) are preferentially recognized.