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Table 6 HBAT-e analyses using ANKH markers in four haplotype blocks defined in HapMap

From: ANKHvariants associated with ankylosing spondylitis: gender differences

Markers in the haplotype block AS nuclear families (n = 226) Testing specifically for affected women Testing specifically for affected men
Additive model
   rs26307, rs27356 [C,C]; 0.78; 39; 0.04 NS [C,C]; 0.79; 24; 0.014
   3088132, rs153929 NS NS NS
   rs28006, rs25957 NS [T,G]; 0.25; 19; 0.007 NS
   ANKH-OR, D5S1991 [1,2]; 0.43; 57; 0.013 NS NS
Recessive/dominant model
   rs26307, rs27356 [C,C]; 0.78; 40; 0.02 NS [C,C]; 0.79; 25; 0.004*
   3088132, rs153929 [G,A]; 0.70; 32; 0.02 NS NS
   rs28006, rs25957 NS [C,C]; 0.71; 18; 0.004* NS
   ANKH-OR, D5S1991 NS NS NS
  1. Data are expressed as [allele]; allele frequency; number of informative families; P value.
  2. *Significant P value after Bonferroni correction. (Because eight tests [four haplotypes and two models] were carried out in the haplotype-based association testing [HBAT]-e analyses, P < 0.00625 [0.05/8] is considered statistically significant.) AS, ankylosing spondylitis; NS, not significant.