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Table 7 FBAT-e analyses considering 226 ankylosing spondylitis nuclear families (201 pedigrees, 894 persons): summary of results using setafftrait 1 -1 0

From: ANKHvariants associated with ankylosing spondylitis: gender differences

Marker Allele Allele frequency Number of informative families Z score P
Additive model: biallelic test
   D5S1953 1 0.56 63 0.15 0.879
   rs26307 C 0.81 35 1.29 0.195
   rs27356 C 0.80 39 1.12 0.261
   3088132 G 0.79 29 0.69 0.489
   rs153929 G 0.24 52 0.61 0.541
   rs258215 T 0.41 41 0.46 0.638
   rs28006 T 0.26 44 1.69 0.090
   rs25957 G 0.23 39 0.90 0.366
   ANKH-OR 1 0.48 80 0.20 0.841
   D5S1991 1 0.52 80 0.29 0.769
   D5S1954 2 0.36 63 1.21 0.227
Recessive model: biallelic test
   D5S1953 1 0.56 46 -0.89 0.370
   rs26307 C 0.81 37 2.17 0.030*
   rs27356 C 0.80 41 1.91 0.055
   3088132 G 0.79 29 1.17 0.240
   rs153929 G 0.24 18 0.55 0.582
   rs258215 A 0.59 29 -0.75 0.453
   rs28006 C 0.74 40 -1.13 0.186
   rs25957 C 0.77 36 -0.66 0.507
   ANKH-OR 2 0.52 50 -0.34 0.733
   D5S1991 2 0.49 52 -0.28 0.779
   D5S1954 1 0.64 61 -1.53 0.126
  1. *Statistically significant findings. FBAT, family-based association testing.