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Table 8 FBAT-e analyses considering 108 ankylosing spondylitis nuclear families (94 pedigrees, 425 persons) in which both affected men and women are present in each family: summary of the results using setafftrait 1 -1 0

From: ANKHvariants associated with ankylosing spondylitis: gender differences

Marker Allele Allele frequency Number of informative families Z score P
Additive model: biallelic test
   D5S1953 1 0.56 39 0.77 0.437
   rs26307 C 0.90 10 0.50 0.617
   rs27356 C 0.77 17 0.15 0.875
   3088132 C 0.21 13 0.63 0.527
   rs153929 G 0.23 32 0.81 0.418
   rs258215 T 0.49 21 1.62 0.104
   rs28006 T 0.29 27 2.81 0.004*
   rs25957 G 0.32 22 2.37 0.017*
   ANKH-OR 1 0.48 51 0.25 0.801
   D5S1991 2 0.50 48 0.13 0.891
   D5S1954 2 0.33 31 1.13 0.254
Recessive model: biallelic test
   D5S1953 2 0.44 31 -1.34 0.177
   rs26307 C 0.79 19 1.00 0.314
   rs27356 C 0.80 20 1.17 0.239
   3088132 G 0.79 14 -0.26 0.788
   rs153929 G 0.23 10 1.06 0.288
   rs258215 A 0.51 12 -2.49 0.012*
   rs28006 C 0.71 20 -2.344 0.019*
   rs25957 C 0.67 15 -1.97 0.048*
   ANKH-OR 1 0.48 27 0.83 0.406
   D5S1991 2 0.49 29 0.98 0.322
   D5S1954 1 0.66 31 -1.67 0.093
  1. *Statistically significant findings. FBAT, family-based association testing.