ANKHvariants associated with ankylosing spondylitis: gender differences

Table 8 FBAT-e analyses considering 108 ankylosing spondylitis nuclear families (94 pedigrees, 425 persons) in which both affected men and women are present in each family: summary of the results using setafftrait 1 -1 0

Marker	Allele	Allele frequency	Number of informative families	Z score	P
Additive model: biallelic test
D5S1953	1	0.56	39	0.77	0.437
rs26307	C	0.90	10	0.50	0.617
rs27356	C	0.77	17	0.15	0.875
3088132	C	0.21	13	0.63	0.527
rs153929	G	0.23	32	0.81	0.418
rs258215	T	0.49	21	1.62	0.104
rs28006	T	0.29	27	2.81	0.004*
rs25957	G	0.32	22	2.37	0.017*
ANKH-OR	1	0.48	51	0.25	0.801
D5S1991	2	0.50	48	0.13	0.891
D5S1954	2	0.33	31	1.13	0.254
Recessive model: biallelic test
D5S1953	2	0.44	31	-1.34	0.177
rs26307	C	0.79	19	1.00	0.314
rs27356	C	0.80	20	1.17	0.239
3088132	G	0.79	14	-0.26	0.788
rs153929	G	0.23	10	1.06	0.288
rs258215	A	0.51	12	-2.49	0.012*
rs28006	C	0.71	20	-2.344	0.019*
rs25957	C	0.67	15	-1.97	0.048*
ANKH-OR	1	0.48	27	0.83	0.406
D5S1991	2	0.49	29	0.98	0.322
D5S1954	1	0.66	31	-1.67	0.093

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