Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy

Table 2 SELDI-TOF MS unpaired serum protein peaks differentially expressed in SJIA before and after conventional therapy

Differences between mass spectra of pretreatment sera of 8 patients who went on to respond to conventional therapy compared with post-treatment sera of 15 patients who responded poorly to conventional therapy. Only variables with nonparametric P values of <0.001 are listed, from 272 peak clusters surveyed. These peaks may represent a profile predictive of response or nonresponse to conventional therapy. SELDI-TOF MS, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry; SJIA, systemic juvenile idiopathic arthritis.

ISSN: 1478-6362