Changes in composite scores in relation to ACR response. Changes in (a) Disease Activity Score (DAS)28, (b) Simplified Disease Activity Index (SDAI) and (c) Clinical Disease Activity Index (CDAI) in relation to the achieved American College of Rheumatology (ACR) response of 91 patients in the inception cohort. ACR ranges were defined as ACR <20 (n = 28, 30.8%), ACR 20–69 (n = 20, 22.0%) and ACR ≥ 70 (n = 43, 47.2%), allowing analysis of independent observations. Error bars span the 95% confidence interval of the mean. Differences in group changes were statistically significant for all three scores (P < 0.0001, one-way analysis of variance). Presented P values for post hoc pairwise group comparisons are subjected to Bonferroni adjustment. *P < 0.0001 for ≥ ACR70 group compared with other groups.