Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specimens

Table 1 Characteristics of studied patients with early (E) and long-standing (L) rheumatoid arthritis (RA)

Patient	Age	Sex	Disease duration	ACR criterion nos. fulfilled^a	Number of samples	Macroscopic signs of synovitis
With early RA
E-01	51	F	11 months	1, 2, 3, 4	13	Vi, Ve
E-02	50	F	2 months	1, 2, 3, 4, 6	8	Vi, Ve
E-03	34	F	4 months	1, 2, 3, 4, 7	8	Vi, Ve
E-04	34	F	3 months	1, 2, 3, 4, 6, 7	13	Vi, Ve
E-05	77	F	2 months	1, 2, 3, 4, 7	11	Vi
E-06	50	M	4 months	1, 2, 3, 4	11	Vi, Ve
E-07	37	F	7 months	1, 2, 3, 4, 6	6	Ve
E-08	61	F	2 months	1, 2, 3, 4	7	Vi
E-09	75	F	4 months	1, 4, 6	12	Vi, Ve, Gr
E-10	25	F	12 months	1, 2, 3, 4	12	Vi, Ve, Gr
E-11	54	M	12 months	1, 2, 3, 4, 6	11	Ve
E-12	60	F	4 months	1, 2, 3, 4, 6	13	Vi, Ve, Gr
With long-standing RA
L-01	54	M	9 years	1, 2, 3, 4, 6, 7	6	Vi, Ve, Gr
L-02	77	M	5 years	1, 2, 3, 4, 5, 6, 7	8	Vi, Ve, Gr
L-03	54	F	7 years	1, 2, 3, 4, 6, 7	6	Vi, Ve
L-04	55	F	3 years	1, 2, 3, 4, 6, 7	11	Vi, Ve, Gr

^aACR (American College of Rheumatology) criteria: 1, morning stiffness; 2, arthritis of three or more joint areas; 3, arthritis of hand joints; 4, symmetric arthritis; 5, rheumatoid nodules; 6, serum rheumatoid factor; 7, radiographic changes. F, female; Gr, granulation; M, male; Ve, increased number of vessels; Vi, villi.

ISSN: 1478-6362