Skip to main content

Table 1 Clinical characteristics of SLE patients according to psychiatric symptoms and anti-Nedd5 C-ter IgG

From: Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations

 

Group Aa (n = 17)

Group Ba (n = 34)

Characteristic

Anti-Nedd5 C-ter IgG (n = 8)

No anti-Nedd5 C-ter IgG (n = 9)

Anti-Nedd5 C-ter IgG (n = 6)

No anti-Nedd5 C-ter IgG (n = 28)

Age (y), mean (range)

38.6 (26–52)

37.1 (23–50)

34.5 (28–48)

37.2 (14–70)

Sex (males/females)

1/7

2/7

1/5

3/25

Disease duration (y), mean (range)

11.2 (7–21)

6.8 (0.5–19)

9 (5–15)

12.1 (0.5–24)

Arthritis, no. (%)

5 (62.5)

9 (100)

5 (83.3)

18 (64.2)

Neurological involvement, no. (%)

2 (25)

4 (44.4)

2 (33.3)

11 (39.2)

Renal involvement, no. (%)

3 (37.5)

0

3 (50)

9 (32.1)

Cytopenia, no. (%)

5 (62.5)

7 (77.7)

4 (66.6)

16 (57.1)

Serositis, no. (%)

2 (25)

2 (22.2)

2 (33.3)

8 (28.5)

SLEDAI >3, no. (%)

5 (62.5)

4 (44.4)

4 (66.6)

12 (42.8)

  1. aGroup A, patients with depression or psychosis; group B, patients without psychiatric manifestations other than anxiety. Differences between the groups as measured by the χ2 test were not statistically significant. SLE, systemic lupus erythematosus; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index.