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Figure 3 | Arthritis Research & Therapy

Figure 3

From: NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-γ-stimulated immune complex arthritis

Figure 3

Expression of macrophage marker F4/80 in knee joints of day 7 IFN-γ-stimulated ICA. Note that 70 to 80% of the infiltrated cells within the synovium consist of macrophages (a). Arrowheads in (b) indicate F4/80-positive macrophages attached to the cartilage surface and found in the lacunae of erosion pits. Original magnification × 400. F, femur; JS, joint space.

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