Skip to main content

Table 2 Effect of VIP treatment of mice with collagen-induced arthritis

From: Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis

  Clinical score Cartilage destruction Bone erosion
CIA 5.08 ± 0.24 2.8 ± 0.07 2.13 ± 0.12
CIA + VIP 1.56 ± 0.17a 0.61 ± 0.22a 0.25 ± 0.11a
  1. Clinical score (mean ± SEM) was assessed on a scale of 0 to 6. Cartilage destruction and bone erosion (mean ± SEM) was graded on a scale from 0 to 3. On day 10 of vasoactive intestinal peptide (VIP) treatment, differences between the arthritic group and the collagen-induced arthritis (CIA) group treated with VIP were statistically significant (ap < 0.001).