Figure 2From: ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritisSchematic representation of the structural and evolutionary relationship of the 19 human ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) gene products. The dendrogram was calculated with ClustalW 1.7 [7]. The structural representation of ADAMTS proteins was adapted from [81]. Where applicable the long form of splice variants is shown (see the text). CS, chondroitin sulphate; CUB, complement C1r/C1s, Uegf (epidermal growth factor-related sea urchin protein) and BMP-1 (bone morphogenic protein-1); PLAC, protease and lacunin; TSR, thrombospondin I-like repeat; vWFCP, von Willebrand factor-cleaving protease.Back to article page