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Table 2 CXCL12 increases and AMD3100 inhibits osteoclast activity

From: Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis

  Number of pits with indicated resorption areaa
In vitro stimulationb 50–100 μm2 100–500 μm2 500–1,000 μm2 1,000–5,000 μm2 >5,000 μm2
Control 481 1,002 166 153 22
CXCL12 848 1,854 382 346 90
CXCL12 + AMD3100 598 1,143 193 164 5
AMD3100 580 1,008 171 140 6
  1. aThe table shows the number of osteoclast resorption pits for five different surface intervals. bSplenocytes of collagen type II/complete Freund's adjuvant-immunized mice were cultured as described in the legend of Fig. 8, and the resorbed area was measured.