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Table 1 Effect of repeated Ad-FasL or Ad-LacZ treatment on the weight of RA synovium

From: Elimination of rheumatoid synovium in situusing a Fas ligand 'gene scalpel'

Ad-LacZ treated Ad-FasL treated
Weight (mg) Rank no. Weight (mg) Rank no.
162.00 16 17.00 4
122.00 13 72.00 11
171.00 17 29.00 6
159.00 15 62.00 9
203.00 20 11.00 3
184.00 19 46.00 8
98.00 12 34.00 7
177.00 18 10.00 2
156.00 14 0.00 1
68.00 10 25.00 5
n1 = 10 T1 = 154 n2 = 10 T2 = 56
P < 0.005 (Rank sum testa)
  1. The repeated gene transfer of recombinant FasL adenovirus (Ad-FasL) and LacZ adenovirus (Ad-LacZ) into rheumatoid arthritis (RA) synovium in severe combined immunodeficiency (SCID) mice are the same as described in Fig. 5. Ten samples per treatment group were examined. After two months of treatment with viruses, the RA synovium samples were collected. The weight of each sample was measured individually for each group. aThe rank sum test was used to determine the P-value (P < 0.005).