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Table 4 PTPN22-1858 C/T genotypes distribution according to the HLA-DRB1 shared epitope (SE)

From: Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele

 

PTPN22 C/T or T/T

PTPN22 C/C

P

TDT RA sample 1

  

0.88

   HLA-DRB1*SE/SE

10

16

 

   HLA-DRB1*SE/X

18

34

 

   HLA-DRB1*X/X

7

15

 

TDT RA sample 2

  

0.16

   HLA-DRB1*SE/SE

13

17

 

   HLA-DRB1*SE/X

14

35

 

   HLA-DRB1*X/X

4

17

 

All TDT RA families

  

0.25

   HLA-DRB1*SE/SE

23

33

 

   HLA-DRB1*SE/X

32

69

 

   HLA-DRB1*X/X

11

32

 
  1. HLA-DRB1*SE/SE, two shared epitopes; HLA-DRB1*SE/X, one shared epitope; HLA-DRB1*X/X, zero shared epitope.
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Arthritis Research & Therapy

ISSN: 1478-6362

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