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Table 1 Patient demographics for the safety population

From: Open label phase II trial of single, ascending doses of MRA in Caucasian children with severe systemic juvenile idiopathic arthritis: proof of principle of the efficacy of IL-6 receptor blockade in this type of arthritis and demonstration of prolonged clinical improvement

 

MRA

 

2 mg/kg (n = 6)

4 mg/kg (n = 6)

8 mg/kg (n = 6)

Age (years)

   

   Mean ± SD

6.3 ± 3.33

7.7 ± 5.13

4.8 ± 1.83

   Median

6.5

6.5

5.0

   Range

3, 10

3, 17

2, 7

Gender

   

   Male (n)

3

6

1

   Female (n)

3

0

5

Race

   

   Caucasian (n)

6

6

6

Weight (kg)

   

   Mean ± SD

23.47 ± 10.954

27.45 ± 14.479

19.63 ± 4.286

   Median

17.95

24.05

19.90

   Range

13.8, 38.0

16.2, 55.5

14.6, 23.6

Height (cm)

   

   Mean ± SD

108.3 ± 14.07

117.5 ± 23.84

108 ± 12.92

   Median

105.5

111.5

102.0

   Range

90, 126

95, 159

94, 127

  1. SD, standard deviation.