Figure 2From: Segregation of a M404V mutation of the p62/sequestosome 1 (p62/SQSTM1) gene with polyostotic Paget's disease of bone in an Italian familyEvidence of PDB in two affected subjects from F01 family. (a) Bone deformity of the right forearm of family member II-3. Relatives described him as having suffered from multiple bone deformities and pain. (b) X-ray scan of the right tibia of family member III-3, with a typical flame-shaped lytic wedge (arrow).Back to article page