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Table 2 Frequencies of HLA-DRB1 alleles in patients with ExRA compared with patients with non-extra-articular RA

From: The impact of HLA-DRB1genes on extra-articular disease manifestations in rheumatoid arthritis

HLA-DRB1 allele Allele frequency P
  ExRA Non-ExRA  
DRB1*01 0.119 0.130 0.74
DRB1*03 0.071 0.113 0.12
DRB1*0401 0.326 0.263 0.09
DRB1*0404 0.119 0.085 0.14
DRB1*0405 0.019 0.003 0.01
Non-SE DRB1*04 0.019 0.045 0.09
DRB1*07 0.052 0.065 0.54
DRB1*08 0.013 0.014 1.00
DRB1*09 0.023 0.011 0.23
DRB1*10 0.016 0.020 0.73
DRB1*11 0.036 0.054 0.28
DRB1*12 0.023 0.003 0.02
DRB1*13 0.042 0.045 0.83
DRB1*15 0.097 0.110 0.65
  1. Global: P = 0.19. ExRA, extra-articular rheumatoid arthritis; SE, shared epitope.