From: Vitamin D receptor gene polymorphisms and susceptibility of hand osteoarthritis in Finnish women
Genotype | Overall OA | Symmetrical OA | Osteophyte | |||
---|---|---|---|---|---|---|
Yes/no | Odds ratio (95% CI)a | Yes/no | Odds ratio (95% CI)a | Yes/no | Odds ratio (95% CI)a | |
ApaIb | ||||||
AA | 51/123 | 1.0 | 29/145 | 1.0 | 18/156 | 1.0 |
Aa | 77/191 | 0.98 (0.62–1.54) | 56/212 | 1.43 (0.84–2.42) | 14/254 | 0.46 (0.21–1.00) |
aa | 32/69 | 1.20 (0.67–2.15) | 25/76 | 1.93 (1.00–3.70) | 7/94 | 0.65 (0.24–1.75) |
'A' allele carriage | 128/303 | 0.82 (0.49–1.37) | 85/357 | 0.65 (0.37–1.13) | 32/410 | 1.01 (0.40–2.51) |
'a' allele carriage | 109/260 | 1.03 (0.67–1.59) | 81/288 | 1.55 (0.94–2.56) | 21/348 | 0.51 (0.25–1.03) |
TaqIc | ||||||
tt | 20/44 | 1.00 | 11/53 | 1.0 | 7/57 | 1.0 |
Tt | 68/173 | 0.75 (0.39–1.44) | 42/199 | 0.90 (0.41–1.97) | 13/228 | 0.46 (0.16–1.26) |
TT | 71/164 | 0.92 (0.48–1.76) | 57/178 | 1.53 (0.72–3.29) | 19/216 | 0.73 (0.27–1.93) |
't' allele carriage | 88/217 | 0.87 (0.58–1.30) | 53/252 | 0.60 (0.38–0.94) | 20/285 | 0.77 (0.39–1.53) |
'T' allele carriage | 139/337 | 0.83 (0.45–1.54) | 99/377 | 1.19 (0.57–2.47) | 32/444 | 0.58 (0.23–1.46) |