Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes

Table 9 Role of severe meniscal extrusion in joint space width and global cartilage volume changes over time

Severe extrusion^a	Absence (n = 72)	Presence (n = 38)
Joint space width (mm)
Baseline	3.09 ± 0.56	2.45 ± 0.53^b
Change at 12 months	-0.05 ± 0.42	-0.07 ± 0.38^c
Change at 24 months	-0.09 ± 0.40	-0.22 ± 0.51^c
Global cartilage volume Loss (%)
Change at 12 months	-3.27 ± 2.96	-4.62 ± 3.43^d
Change at 24 months	-4.79 ± 4.00	-8.19 ± 5.05^b

Values are mean ± standard deviation. ^aSevere = complete meniscal extrusion. ^bp = 0.001. ^cp = not significant. ^dp = 0.02, two samples Student t test comparing the absence versus presence of severe extrusion.

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