Table 1 Grading of kidney lesions
Score | Glomerulonephritis | Interstitial nephritis | Vessels |
|---|---|---|---|
1+ | Focal, mild or early proliferative | 1–3 small foci (5–10 cells) of MNC * | MNC around renal pelvis/blood vessels |
2+ | Multifocal proliferative with increased matrix and inflammatory cells | Mild MNC infiltrates around individual tubules; isolated atrophied tubules | MNC infiltrates around main arteries; small foci 10–20 cells of MNC around interlobular arteries |
3+ | Diffuse proliferative | More extensive infiltrates with large foci of tubular atrophy | Individual foci of MNC around small arterial branches more extensive |
4+ | Extensive sclerosis/ crescents: proteinuria | Extensive MNC infiltrates between tubules; extensive tubule atrophy/necrosis | MNC infiltrates extend into surrounding parenchyma/most vessels affected/vasculitis |