Figure 4
Western blot analysis of key signaling proteins downstream to A3 adenosine receptor (A3AR) activation in DLN extracts. (a) DLN cells derived from naïve and adjuvant-induced arthritis (AIA) animals. (b) DLN cells derived from AIA animals compared with AIA animals treated with IB-MECA. (c) PKB/Akt activity utilizing GSK-3β as a substrate in AIA animals in comparison with AIA animals treated with IB-MECA.