Skip to main content

Table 1 Severity of arthritis and anti-collagen type II (anti-CII) titers in (NFR/N × B10.Q) × B10.Q female mice and parental strains

From: Identification of collagen-induced arthritis loci in aged multiparous female mice

Generation n Day of onset (range)a Maximum scoreb Anti-CII titers (± standard error) (mg/ml) on day 100
F0 NFR/N 20 76.0 (11–102) 4.0 ± 1 1.53 ± 0.37c
F0 B10.Q 19 49.5 (12–69) 4.0 ± 1 0.87 ± 0.11
(NFR/N × B10.Q) × B10.Q 200 56.0 (8–105) 6.0 ± 0.2 1.63 ± 0.18
  1. aMedian value on the days of onset when calculated in all arthritic mice in the group on day 100 (maximum–minimum values in the series).
  2. bMean ± standard error of the maximum score from all arthritic mice in the respective group.
  3. cSignificantly higher than in B10.Q mice (P = 0.02 in Student's unpaired t test).