Table 3 Distribution of genotypes between affected and unaffected N2 mice at different loci linked to clinical phenotypes of collagen-induced arthritis
From: Identification of collagen-induced arthritis loci in aged multiparous female mice
Trait | Locus | Location (cM) | Affected | Unaffected | LOD | ||
|---|---|---|---|---|---|---|---|
Homozygote for B10.Q | Heterozygote | Homozygote for B10.Q | Heterozygote | ||||
Incidence at day 100 | D1Mit161 | 27.0 | 36 (71%) | 15 (29%) | 70 (48%) | 75 (52%) | 2.8* |
D11Mit70 | 54.0 | 30 (58%) | 21 (31%) | 49 (34%) | 96 (66%) | 2.7* | |
D11Mit99 | 59.5 | 35 (69%) | 16 (31%) | 50 (35%) | 95 (65%) | 4.0** | |
D11Mit360 | 64.0 | 37 (73%) | 14 (27%) | 46 (31%) | 99 (68%) | 4.1** | |
D11Mit258 | 65.0 | 36 (71%) | 15 (29%) | 49 (34%) | 96 (66%) | 4.1** | |
D11Mit333 | 66.0 | 36 (71%) | 15 (29%) | 48 (33%) | 97 (67%) | 4.1** | |
D11Mit181 | 69.0 | 37 (73%) | 14 (27%) | 48 (33%) | 97 (67%) | 4.1** | |
D11Mit214 | 70.0 | 39 (76%) | 12 (24%) | 55 (38%) | 90 (62%) | 4.0* | |