Skip to main content

Table 3 Distribution of genotypes between affected and unaffected N2 mice at different loci linked to clinical phenotypes of collagen-induced arthritis

From: Identification of collagen-induced arthritis loci in aged multiparous female mice

Trait Locus Location (cM) Affected Unaffected LOD
    Homozygote for B10.Q Heterozygote Homozygote for B10.Q Heterozygote  
Incidence at day 100 D1Mit161 27.0 36 (71%) 15 (29%) 70 (48%) 75 (52%) 2.8*
  D11Mit70 54.0 30 (58%) 21 (31%) 49 (34%) 96 (66%) 2.7*
  D11Mit99 59.5 35 (69%) 16 (31%) 50 (35%) 95 (65%) 4.0**
  D11Mit360 64.0 37 (73%) 14 (27%) 46 (31%) 99 (68%) 4.1**
  D11Mit258 65.0 36 (71%) 15 (29%) 49 (34%) 96 (66%) 4.1**
  D11Mit333 66.0 36 (71%) 15 (29%) 48 (33%) 97 (67%) 4.1**
  D11Mit181 69.0 37 (73%) 14 (27%) 48 (33%) 97 (67%) 4.1**
  D11Mit214 70.0 39 (76%) 12 (24%) 55 (38%) 90 (62%) 4.0*
  1. *Suggestive significance, **significant.