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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis

Figure 2

Expression of BMP-4 and BMP-5 in synovial tissues detected by microarray technique. Results are presented on a logarithmic scale with maximum, minimum, quartiles and median. Where indicated with an asterisk, there were significant differences from normal tissues (p < 0.05; t test). Rheumatoid arthritis (RA) versus normal donors (ND): bone morphogenetic protein (BMP)-4, p = 0.0009 (adjusted p ≤ 0.0083); BMP-5, p = 0.0142 (probe set ID 205431_s_at; data not shown) and p = 0.006 (probe set ID 205430_at) (adjusted p ≤ 0.009). Osteoarthritis (OA) versus ND: BMP-4, p = 0.854; BMP-5, p = 0.216 (probe set ID 205431_s_at) and p = 0.129 (probe set ID 205430_at) (no significance). RA versus OA: BMP-4, p = 0.000003 (adjusted p ≤ 0.0083); BMP-5, p = 0.2391 (probe set ID 205431_s_at) and p = 0.026 (probe set ID 205430_at) (no significance).

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Arthritis Research & Therapy

ISSN: 1478-6362

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