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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis

Figure 4

Immunohistochemistry and in situ hybridization of synovial tissues for BMP-4. In normal synovial tissue the expression of bone morphogenetic protein (BMP) is localized to the synovial lining layer. In rheumatoid arthritis (RA) and osteoarthritis (OA) tissue samples BMP-4 is expressed less by cells of the superficial synovial layer but more by cells scattered in deeper layers. Original magnifications: immunohistochemistry (IMH): RA, normal donors (ND) ×40, OA ×20; in situ hybridization (ISH): RA, OA, ND ×40.

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Arthritis Research & Therapy

ISSN: 1478-6362

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