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Table 6 Post-treatment increases in NCI CTC v3.0 toxicity grades from baseline values

From: Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus

Labparameter No increase Toxicity increase
   1 grade 2–3 grades
Hematology    
   Hemoglobin 10 4 0
   Platelets 12 2 0
   WBC 11 3 0
   ALC 6 6 2
   ANC 13 1 0
Chemistry    
   Creatinine 10 4 0
   Total Bilirubin 14 0 0
   Alkaline phosphatase 12 2 0
   ALT (SGPT) 9 5 0
   AST (SGOT) 10 4 0
   GGT 12 2 0
  1. ALC, absolute lymphocyte count, ANC, absolute neutrophil count, ALT, alanine aminotransferase, AST, aspartate aminotransferase, GGT, gamma glutamyl transferase, WBC, white blood cell