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Table 6 Post-treatment increases in NCI CTC v3.0 toxicity grades from baseline values

From: Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus

Labparameter

No increase

Toxicity increase

  

1 grade

2–3 grades

Hematology

   

   Hemoglobin

10

4

0

   Platelets

12

2

0

   WBC

11

3

0

   ALC

6

6

2

   ANC

13

1

0

Chemistry

   

   Creatinine

10

4

0

   Total Bilirubin

14

0

0

   Alkaline phosphatase

12

2

0

   ALT (SGPT)

9

5

0

   AST (SGOT)

10

4

0

   GGT

12

2

0

  1. ALC, absolute lymphocyte count, ANC, absolute neutrophil count, ALT, alanine aminotransferase, AST, aspartate aminotransferase, GGT, gamma glutamyl transferase, WBC, white blood cell