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Table 1 Characteristics of the study population

From: Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs

Characteristic Group P value
  Repair observed Repair not observed  
Patients (n) 13 109  
Female (n [%]) 10 (76.9%) 93 (85.3%) NSa
Age (mean [range]; years) 64.2 ± 9.8 (39–78) 60.6 ± 12.6 (22–85) NSb
Disease duration (mean [range]; years) 12.5 ± 9.6 (2.7–38) 14.3 ± 10.8 (1–45) NSc
RF positivity (n [%]) 11(84.6%) 85(78.0%) NSa
Dosage of prednisone (mean [range]; mg) 2.0 ± 2.1 (0.0–6.0) 3.7 ± 3.3 (0.0–14.5) NSc
Prescribed bisphosphonate (n [%]) 8 (61.5%) 79 (72.5%) NSa
Functional class
   I 4 10 <0.01c
   II 9 78  
   III 0 18  
   IV 0 3  
RA stage
   I 0 0 NSc
   II 4 36  
   III 2 19  
   IV 7 54  
DAS28-3 score at baseline (mean [range]) 4.4 ± 1.2 (2.7–6.0) 4.0 ± 1.1 (1.0–7.0) NSb
DAS28-3 score at follow up (mean [range]) 2.7 ± 1.1 (1.5–5.4) 3.7 ± 1.2 (0.2–8.1) <0.005b
ΔDAS28-3 (mean [range]) -1.7 ± 1.2 (-3.5 to +0.1) -0.3 ± 1.0 (-2.4 to +2.6) <0.001b
Time interval between pairs of radiographs, years (mean [range]) 2.3 ± 1.0 (1.4–3.1) 1.6 ± 1.8 (1.0–1.6) NSb
ΔDAS28-3/year (mean [range]) -0.9 ± 0.8 (-2.6 to +0.1) -0.2 ± 0.9 (-2.8 to +3.4) <0.01b
  1. RA functional status was determined using American College of Rheumatology criteria, and RA stage was determined using Steinbrocker criteria. aFisher's exact probability test; bStudent's t test; cMann-Whitney U test. DAS, Disease Activity Score; RF, rheumatoid factor.