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Table 2 Results of the odds ratio calculation on the replication sample (sample B)

From: Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis

Genotypes Genotype distribution (n [%]) Odds ratio 95% Confidence interval
  RA index (n = 100) Pseudo-controlsa (n = 300)   
S2/S2 9 (9) 11 (3.6) 18.0 4.5–71.1
S2/S3P 19 (19) 17 (5.7) 19.5 6.6–57.2
S2/L 23 (23) 63 (21) 5.3 2.0–13.9
S3P/S3P 5 (5) 7 (2.3) 8.7 2.1–36.9
S3P/L 25 (25) 77 (25.7) 3.1 1.4–6.9
L/L 19 (19) 125 (41.7) 1 -
  1. Alleles S2, S3P and L are defined according to amino acid sequence at positions 70–74, as described in Table 1. The L alleles are the low-risk alleles S1, S3D and X. The reference genotype is L/L. aPseudo-controls are the three other genotypes that could be formed by the parental genotypes.