Table 2 Non-steroidal anti-inflammatory drugs, corticosteroids and bisphosphonates during lactation
From: Anti-inflammatory and immunosuppressive drugs and reproduction
Drug | Secretion into breast milk | Effect on nursing infant | Breastfeeding allowed |
|---|---|---|---|
Non-steroidal anti-inflammatory drugs | In low concentrations | No adverse effects | Diclofenac, flufenamic acid, ibuprofen, indomethacin, ketorolac, mefenamic acid, naproxen and piroxicam are compatible with breastfeeding [41-43] |
Prednisone | 0.025% of maternal dose | No adverse effects | Compatible with breastfeeding [84,85] |
Dexamethasone | Not studied | Not known | Avoid |
Betamethasone | Not studied | Not known | Avoid |
Bisphosphonates | Pamidronate not detected, no reports on other bisphosphonates | No adverse effect in one case [91] | Insufficient data. Risk-benefit must be weighed before breastfeeding |