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Table 2 Non-steroidal anti-inflammatory drugs, corticosteroids and bisphosphonates during lactation

From: Anti-inflammatory and immunosuppressive drugs and reproduction

Drug Secretion into breast milk Effect on nursing infant Breastfeeding allowed
Non-steroidal anti-inflammatory drugs In low concentrations No adverse effects Diclofenac, flufenamic acid, ibuprofen, indomethacin, ketorolac, mefenamic acid, naproxen and piroxicam are compatible with breastfeeding [41-43]
Prednisone 0.025% of maternal dose No adverse effects Compatible with breastfeeding [84,85]
Dexamethasone Not studied Not known Avoid
Betamethasone Not studied Not known Avoid
Bisphosphonates Pamidronate not detected, no reports on other bisphosphonates No adverse effect in one case [91] Insufficient data. Risk-benefit must be weighed before breastfeeding