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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts

Figure 1

Statins decrease the viability of synovial fibroblasts in a concentration-dependent manner. Synovial fibroblasts from a patient with rheumatoid arthritis were cultured for 96 hours in the presence of 1, 3 or 10 μM lovastatin, atorvastatin, simvastatin or cerivastatin. XTT assays were then performed on quadruplicate wells to determine the percentage cellular viability of statin-treated cultures in comparison with those treated with the vector. Results are representative of two experiments.

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