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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts

Figure 2

Statins decrease the viability of synovial fibroblasts in a time-dependent manner. Synovial fibroblasts were cultured for 24, 48, 72 and 96 hours in the presence of 10 μM atorvastatin, 10 μM simvastatin or 3 μM cerivastatin. XTT assays were then performed on quadruplicate wells to determine the percentage cellular viability of statin-treated cultures in comparison with those treated with the vector under identical conditions. Results are representative of two experiments.

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