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Figure 4 | Arthritis Research & Therapy

Figure 4

From: The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus

Figure 4

FACS analysis of four heterogeneous nuclear ribonucleoprotein (hnRNP)-A2 specific T cell clones (TCCs) derived from systemic lupus erythematosus (SLE) patients. Left panels: clones were stained with fluorescein isothiocyanate (FITC)- or phycoerythrin-conjugated mAbs against CD4 or CD8, respectively. Right panels: clones were stained with a FITC-conjugated anti-CD28 mAb and a phycoerythrin-conjugated control mAb. Top panel: FACS profile of a CD4+ CD28- TCC. Second panel: FACS profile of a CD4+CD28+ TCC. Third panel: FACS profile of a CD8+ CD28- TCC. Bottom panel: FACS profile of a CD8+ CD28+ TCC.

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