Figure 4

Effect of hepatocyte growth factor (HGF) on cytokine gene expression by chronic graft-versus-host disease (GVHD) mice. Chronic GVHD mice were treated as described in Figure 1. At 2 weeks after GVHD induction, spleen, liver, and kidneys were removed and IFN-γ and IL-4 mRNA expression determined by RT-PCR analysis. Data represent mean ± SD for four mice per group. *p < 0.05 compared to untreated GVHD.