Table 1 IDDM8 single nucleotide polymorphism allele frequencies in 180 rheumatoid arthritis cases and 180 controls
From: Fine mapping of genes within the IDDM8region in rheumatoid arthritis
SNP | Gene | Allele frequencies in RA cases | Allele frequencies in controls | OR (95 percent CI) | P value | Genotype frequencies in RA cases | Genotype frequencies in controls | P valuea |
|---|---|---|---|---|---|---|---|---|
rs11752069 | LOC154449 | C = 0.35 (112) G = 0.65 (204) | C = 0.29 (94) G = 0.71 (234) | 1.37 (0.98–1.9) | 0.065 | CC = 0.11 (17) CG = 0.49 (78) GG = 0.4 (63) | CC = 0.1 (17) CG = 0.37 (60) GG = 0.53 (87) | 0.05 |
rs910424 | KIAA1838 | C = 0.63 (203) T = 0.37 (119) | C = 0.72 (248) T = 0.28 (96) | 1.51 (1.1–2.1) | 0.012 | CC = 0.39 (63) CT = 0.48 (77) TT = 0.13 (21) | CC = 0.52 (90) CT = 0.4 (68) TT = 0.08 (14) | 0.04 |
rs958997 | KIAA1838 | A = 0.9 (289) C = 0.1 (31) | A = 0.86 (290) C = 0.14 (48) | 1.54 (0.96–2.5) | 0.075 | AA = 0.82 (131) AC = 0.17 (27) CC = 0.01 (2) | AA = 0.73 (124) AC = 0.25 (42) CC = 0.02 (3) | 0.18 |
rs2144245 | KIAA1838 | C = 0.87 (245) T = 0.13 (35) | C = 0.82 (252) T = 0.18 (54) | 1.5 (0.95–2.4) | 0.083 | CC = 0.76 (106) CT = 0.24 (33) TT = 0.007 (4) | CC = 0.67 (103) CT = 0.3 (46) TT = 0.03 (4) | 0.18 |
rs1274 | KIAA1838 | A = 0.9 (291) G = 0.1 (31) | A = 0.86 (299) G = 0.14 (49) | 1.54 (0.96–2.5) | 0.076 | AA = 0.82 (132) AG = 0.17 (27) GG = 0.01 (2) | AA = 0.73 (128) AG = 0.25 (43) GG = 0.02 (3) | 0.18 |