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Table 1 IDDM8 single nucleotide polymorphism allele frequencies in 180 rheumatoid arthritis cases and 180 controls

From: Fine mapping of genes within the IDDM8region in rheumatoid arthritis

SNP Gene Allele frequencies in RA cases Allele frequencies in controls OR (95 percent CI) P value Genotype frequencies in RA cases Genotype frequencies in controls P valuea
rs11752069 LOC154449 C = 0.35 (112) G = 0.65 (204) C = 0.29 (94) G = 0.71 (234) 1.37 (0.98–1.9) 0.065 CC = 0.11 (17) CG = 0.49 (78) GG = 0.4 (63) CC = 0.1 (17) CG = 0.37 (60) GG = 0.53 (87) 0.05
rs910424 KIAA1838 C = 0.63 (203) T = 0.37 (119) C = 0.72 (248) T = 0.28 (96) 1.51 (1.1–2.1) 0.012 CC = 0.39 (63) CT = 0.48 (77) TT = 0.13 (21) CC = 0.52 (90) CT = 0.4 (68) TT = 0.08 (14) 0.04
rs958997 KIAA1838 A = 0.9 (289) C = 0.1 (31) A = 0.86 (290) C = 0.14 (48) 1.54 (0.96–2.5) 0.075 AA = 0.82 (131) AC = 0.17 (27) CC = 0.01 (2) AA = 0.73 (124) AC = 0.25 (42) CC = 0.02 (3) 0.18
rs2144245 KIAA1838 C = 0.87 (245) T = 0.13 (35) C = 0.82 (252) T = 0.18 (54) 1.5 (0.95–2.4) 0.083 CC = 0.76 (106) CT = 0.24 (33) TT = 0.007 (4) CC = 0.67 (103) CT = 0.3 (46) TT = 0.03 (4) 0.18
rs1274 KIAA1838 A = 0.9 (291) G = 0.1 (31) A = 0.86 (299) G = 0.14 (49) 1.54 (0.96–2.5) 0.076 AA = 0.82 (132) AG = 0.17 (27) GG = 0.01 (2) AA = 0.73 (128) AG = 0.25 (43) GG = 0.02 (3) 0.18
  1. aP value calculated from chi-squared comparison of genotype frequencies in case versus controls. CI, confidence interval; OR, odds ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism.