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Table 1 IDDM8 single nucleotide polymorphism allele frequencies in 180 rheumatoid arthritis cases and 180 controls

From: Fine mapping of genes within the IDDM8region in rheumatoid arthritis

SNP Gene Allele frequencies in RA cases Allele frequencies in controls OR (95 percent CI) P value Genotype frequencies in RA cases Genotype frequencies in controls P valuea
rs11752069 LOC154449 C = 0.35 (112)
G = 0.65 (204)
C = 0.29 (94)
G = 0.71 (234)
1.37 (0.98–1.9) 0.065 CC = 0.11 (17)
CG = 0.49 (78)
GG = 0.4 (63)
CC = 0.1 (17)
CG = 0.37 (60)
GG = 0.53 (87)
0.05
rs910424 KIAA1838 C = 0.63 (203)
T = 0.37 (119)
C = 0.72 (248)
T = 0.28 (96)
1.51 (1.1–2.1) 0.012 CC = 0.39 (63)
CT = 0.48 (77)
TT = 0.13 (21)
CC = 0.52 (90)
CT = 0.4 (68)
TT = 0.08 (14)
0.04
rs958997 KIAA1838 A = 0.9 (289)
C = 0.1 (31)
A = 0.86 (290)
C = 0.14 (48)
1.54 (0.96–2.5) 0.075 AA = 0.82 (131)
AC = 0.17 (27)
CC = 0.01 (2)
AA = 0.73 (124)
AC = 0.25 (42)
CC = 0.02 (3)
0.18
rs2144245 KIAA1838 C = 0.87 (245)
T = 0.13 (35)
C = 0.82 (252)
T = 0.18 (54)
1.5 (0.95–2.4) 0.083 CC = 0.76 (106)
CT = 0.24 (33)
TT = 0.007 (4)
CC = 0.67 (103)
CT = 0.3 (46)
TT = 0.03 (4)
0.18
rs1274 KIAA1838 A = 0.9 (291)
G = 0.1 (31)
A = 0.86 (299)
G = 0.14 (49)
1.54 (0.96–2.5) 0.076 AA = 0.82 (132)
AG = 0.17 (27)
GG = 0.01 (2)
AA = 0.73 (128)
AG = 0.25 (43)
GG = 0.02 (3)
0.18
  1. aP value calculated from chi-squared comparison of genotype frequencies in case versus controls. CI, confidence interval; OR, odds ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism.