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Table 3 IDDM8 single nucleotide polymorphism allele frequencies in 354 rheumatoid arthritis cases and 372 controls

From: Fine mapping of genes within the IDDM8region in rheumatoid arthritis

SNP Gene Allele frequencies in RA cases Allele frequencies in controls OR (95 percent CI) P value Genotype frequencies in RA cases Genotype frequencies in controls P valuea
rs11752069 LOC154449 C = 0.32 (190)
G = 0.68 (404)
C = 0.31 (215)
G = 0.69 (479)
1.07 (0.84–1.4) 0.57 CC = 0.09 (28)
CG = 0.45 (134)
GG = 0.46 (135)
CC = 0.1 (36)
CG = 0.40 (140)
GG = 0.49 (171)
0.47
rs910424 KIAA1838 C = 0.67 (419)
T = 0.33 (207)
C = 0.70 (493)
T = 0.30 (211)
1.13 (0.89–1.4) 0.3 CC = 0.44 (139)
CT = 0.45 (141)
TT = 0.11 (33)
CC = 0.49 (173)
CT = 0.41 (144)
TT = 0.10 (35)
0.47
rs958997 KIAA1838 A = 0.90 (553)
C = 0.10 (61)
A = 0.87 (606)
C = 0.13 (90)
1.29 (0.9–1.86) 0.13 AA = 0.81 (249)
AC = 0.17 (53)
CC = 0.02 (5)
AA = 0.76 (263)
AC = 0.23 (80)
CC = 0.01 (5)
0.19
rs2144245 KIAA1838 C = 0.88 (514)
T = 0.12 (70)
C = 0.86 (585)
T = 0.14 (95)
1.24 (0.87–1.7) 0.21 CC = 0.78 (229)
CT = 0.20 (59)
TT = 0.02 (4)
CC = 0.74 (252)
CT = 0.24 (82)
TT = 0.02 (6)
0.18
rs1274a KIAA1838 A = 0.9 (291)
G = 0.1 (31)
A = 0.86 (299)
G = 0.14 (49)
1.54 (0.96–2.5) 0.076 AA = 0.82 (132)
AG = 0.17 (27)
GG = 0.01 (2)
AA = 0.73 (128)
AG = 0.25 (43)
GG = 0.02 (3)
0.18
  1. aP value calculated from chi-squared comparison of genotype frequencies in case versus controls. CI, confidence interval; OR, odds ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism.