Table 3 IDDM8 single nucleotide polymorphism allele frequencies in 354 rheumatoid arthritis cases and 372 controls
From: Fine mapping of genes within the IDDM8region in rheumatoid arthritis
SNP | Gene | Allele frequencies in RA cases | Allele frequencies in controls | OR (95 percent CI) | P value | Genotype frequencies in RA cases | Genotype frequencies in controls | P valuea |
|---|---|---|---|---|---|---|---|---|
rs11752069 | LOC154449 | C = 0.32 (190) G = 0.68 (404) | C = 0.31 (215) G = 0.69 (479) | 1.07 (0.84–1.4) | 0.57 | CC = 0.09 (28) CG = 0.45 (134) GG = 0.46 (135) | CC = 0.1 (36) CG = 0.40 (140) GG = 0.49 (171) | 0.47 |
rs910424 | KIAA1838 | C = 0.67 (419) T = 0.33 (207) | C = 0.70 (493) T = 0.30 (211) | 1.13 (0.89–1.4) | 0.3 | CC = 0.44 (139) CT = 0.45 (141) TT = 0.11 (33) | CC = 0.49 (173) CT = 0.41 (144) TT = 0.10 (35) | 0.47 |
rs958997 | KIAA1838 | A = 0.90 (553) C = 0.10 (61) | A = 0.87 (606) C = 0.13 (90) | 1.29 (0.9–1.86) | 0.13 | AA = 0.81 (249) AC = 0.17 (53) CC = 0.02 (5) | AA = 0.76 (263) AC = 0.23 (80) CC = 0.01 (5) | 0.19 |
rs2144245 | KIAA1838 | C = 0.88 (514) T = 0.12 (70) | C = 0.86 (585) T = 0.14 (95) | 1.24 (0.87–1.7) | 0.21 | CC = 0.78 (229) CT = 0.20 (59) TT = 0.02 (4) | CC = 0.74 (252) CT = 0.24 (82) TT = 0.02 (6) | 0.18 |
rs1274a | KIAA1838 | A = 0.9 (291) G = 0.1 (31) | A = 0.86 (299) G = 0.14 (49) | 1.54 (0.96–2.5) | 0.076 | AA = 0.82 (132) AG = 0.17 (27) GG = 0.01 (2) | AA = 0.73 (128) AG = 0.25 (43) GG = 0.02 (3) | 0.18 |