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Table 3 IDDM8 single nucleotide polymorphism allele frequencies in 354 rheumatoid arthritis cases and 372 controls

From: Fine mapping of genes within the IDDM8region in rheumatoid arthritis

SNP Gene Allele frequencies in RA cases Allele frequencies in controls OR (95 percent CI) P value Genotype frequencies in RA cases Genotype frequencies in controls P valuea
rs11752069 LOC154449 C = 0.32 (190) G = 0.68 (404) C = 0.31 (215) G = 0.69 (479) 1.07 (0.84–1.4) 0.57 CC = 0.09 (28) CG = 0.45 (134) GG = 0.46 (135) CC = 0.1 (36) CG = 0.40 (140) GG = 0.49 (171) 0.47
rs910424 KIAA1838 C = 0.67 (419) T = 0.33 (207) C = 0.70 (493) T = 0.30 (211) 1.13 (0.89–1.4) 0.3 CC = 0.44 (139) CT = 0.45 (141) TT = 0.11 (33) CC = 0.49 (173) CT = 0.41 (144) TT = 0.10 (35) 0.47
rs958997 KIAA1838 A = 0.90 (553) C = 0.10 (61) A = 0.87 (606) C = 0.13 (90) 1.29 (0.9–1.86) 0.13 AA = 0.81 (249) AC = 0.17 (53) CC = 0.02 (5) AA = 0.76 (263) AC = 0.23 (80) CC = 0.01 (5) 0.19
rs2144245 KIAA1838 C = 0.88 (514) T = 0.12 (70) C = 0.86 (585) T = 0.14 (95) 1.24 (0.87–1.7) 0.21 CC = 0.78 (229) CT = 0.20 (59) TT = 0.02 (4) CC = 0.74 (252) CT = 0.24 (82) TT = 0.02 (6) 0.18
rs1274a KIAA1838 A = 0.9 (291) G = 0.1 (31) A = 0.86 (299) G = 0.14 (49) 1.54 (0.96–2.5) 0.076 AA = 0.82 (132) AG = 0.17 (27) GG = 0.01 (2) AA = 0.73 (128) AG = 0.25 (43) GG = 0.02 (3) 0.18
  1. aP value calculated from chi-squared comparison of genotype frequencies in case versus controls. CI, confidence interval; OR, odds ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism.