Figure 1
From: Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis
Scatterplots representing the relationship between α-actinin antibody (Ab) binding and levels of anti-double-stranded DNA (anti-dsDNA) Abs in the pre-selected diagnostic groups. The relationship of α-actinin Ab binding with anti-dsDNA Abs detected by enzyme-linked immunosorbent assay (ELISA) (a) or by EliA assay (b) and with overall disease activity (SLEDAI) (c). Broken lines indicate cutoff levels for the respective assays (see Materials and methods for analytical details). EliA, fluorescence enzyme immunoassay test for anti-dsDNA (Phadia GmbH); OD, optical density; Rs, Spearman's rho; SLEDAI, Systemic Lupus Erythematosus Disease activity index.