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Table 1 Demographics and α-actinin binding in the various disease groups

From: Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis

Disease group Female/male ratio (percentage) Age in years (range) OD α-actinin binding (range) No. (percentage) with positive α-actinin binding
RA (n = 68) 65/35 67.7 (24 to 85) 0.102 (0.06 to 0.26)a 8 (12)a
SLE (n = 99) 92/8 35.7 (15 to 73) 0.112 (0.05 to 0.63)a 20 (20)a
WG (n = 85) 57/43 49.1 (17 to 76) 0.053 (0.04 to 0.08) 0 (0)
ANA-positive (n = 142) 63/37 52.2 (6 to 78) 0.09 (0.06 to 0.90) 46 (32)a
  1. aIndicates significant difference compared with WG category. Numbers represent mean values (range) unless otherwise indicated. ANA, anti-nuclear antibody; OD, optical density; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; WG, Wegener's granulomatosis.