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Table 4 Relative signal values of articular cartilage extracellular-matrix-related genes significantly affected by IL-1 and/or glucosamine

From: Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1β

Gene Treatment group
  No glucosamine, no IL-1 Glucosamine, no IL-1 IL-1, no glucosamine Glucosamine with IL-1
A disintegrin and metalloproteinase domain 15 142.9 121.3 64.9 98.3
A disintegrin and metalloproteinase domain 17 434.6 533.1 897.4 616.6
ADAMTS-1 457.0 202.1 996.0 359.7
ADAMTS-4 79.2 149.8 76.0 149.4
Aggrecan-1 162.6 154.7 47.1 117.3
Biglycan 80.9 26.1 126.8 19.2
Cartilage link protein 662.1 284.3 75.9 166.7
Chondroitin sulfate proteoglycan 2 (Versican) 135.3 45.3 418.1 60.0
Collagen type II alpha 1, chain precursor 106.4 42.0 3.8 20.6
Collagen type III alpha 1 2710.2 2720.0 1320.4 2242.6
Collagen type VIII alpha 1 622.6 362.5 857.9 493.8
Collagen type XI alpha 1 2510.6 2090.9 1471.5 1830.9
Laminin α-4 chain precursor 238.3 510.2 158.6 410.8
Matrix metalloproteinase 2 1014.0 1388.4 1825.7 1886.2
Matrix metalloproteinase 3 894.7 1966.4 5787.4 4223.6
Matrix metalloproteinase 9 - 11.1 2194.0 36.5
Matrix metalloproteinase 10 - 7.8 271.2 39.6
Matrix metalloproteinase 12 4.9 13.4 1132.0 84.9
Matrix metalloproteinase 13 268.3 2126.9 4497.4 3871.2
Syndecan 2 1515.8 1292.9 656.8 963.4
Syndecan 4 927.7 796.8 2049.2 1327.5
Thrombospondin 4 precursor 2535.4 2217.7 1224.9 1662.6
TIMP-1 1786.8 1857.2 3049.8 2311.4
TIMP-2 995.9 937.0 726.9 923.1
TIMP-3 1317.1 1983.9 1105.3 1859.0