Skip to main content
Figure 2 | Arthritis Research & Therapy

Figure 2

From: Effects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial cells

Figure 2

Sixty-one probe sets differentially expressed (P < 0.005) among the lipopolysaccharide-challenged groups. Three individual donors are represented for each group. Group 2 (G2), LPS control; group 3 (G3), pretreatment and sustained treatment with lower molecular weight hyaluronan (HA) product; group 4 (G4), pretreatment and sustained treatment with higher molecular weight HA product. Columns represent individual animals 1, 2, and 3. Rows represent probe sets ordered by a hierarchical cluster analysis using the average linkage and 1 – Pearson correlation as the measure of dissimilarity. Shading is indicative of relative expression: white, median expression; deepening shades of red, increasing expression of the probe set above the median value; deepening shades of blue, decreasing expression of the probe set below the median value. *Gene expression differentially expressed (adjusted P < 0.005) between at least one of the pairs of treatments. Probe set found in canines, which was included on the microarray to validate data.

Back to article page