Diplotype configuration | Acetylator phenotype | SLE (n = 166) | PM/DM (n = 39) | Healthy individuals (n = 195) |
---|---|---|---|---|
NAT2*4/*4 | Fast | 84 | 14 | 103 |
NAT2*4/*5B | Fast | 2 | 0 | 0 |
NAT2*4/*5E | Fast | 1 | 0 | 0 |
NAT2*4/*6A | Fast | 43 | 13 | 51 |
NAT2*4/*7B | Fast | 17 | 8 | 24 |
NAT2*4/*13 | Fast | 1 | 0 | 1 |
Fast acetylators | 148 (89.2) | 35 (89.7) | 179 (91.8) | |
NAT2*5B/*5B | Slow | 0 | 0 | 1 |
NAT2*5B/*6A | Slow | 0 | 0 | 2 |
NAT2*5B/*7B | Slow | 1 | 0 | 0 |
NAT2*6A/*6A | Slow | 5 | 2 | 6 |
NAT2*6A/*7B | Slow | 9 | 1 | 6 |
NAT2*7B/*7B | Slow | 3 | 1 | 1 |
Slow acetylators | 18 (10.8) | 4 (10.3) | 16 (8.2) |