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Table 1 Numbers and frequencies of the diplotype configurations at the NAT2 gene among patients with SLE, those with PM/DM and healthy individuals

From: Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus

Diplotype configuration Acetylator phenotype SLE (n = 166) PM/DM (n = 39) Healthy individuals (n = 195)
NAT2*4/*4 Fast 84 14 103
NAT2*4/*5B Fast 2 0 0
NAT2*4/*5E Fast 1 0 0
NAT2*4/*6A Fast 43 13 51
NAT2*4/*7B Fast 17 8 24
NAT2*4/*13 Fast 1 0 1
Fast acetylators 148 (89.2) 35 (89.7) 179 (91.8)
NAT2*5B/*5B Slow 0 0 1
NAT2*5B/*6A Slow 0 0 2
NAT2*5B/*7B Slow 1 0 0
NAT2*6A/*6A Slow 5 2 6
NAT2*6A/*7B Slow 9 1 6
NAT2*7B/*7B Slow 3 1 1
Slow acetylators 18 (10.8) 4 (10.3) 16 (8.2)
  1. Values are expressed as number (%) of patients. NAT2, N-acetyltransferase 2; PM/DM, polymyositis/dermatomyositis; SLE, systemic lupus erythematosus.