Association of cerebrospinal fluid anti-ribosomal P protein antibodies with diffuse psychiatric/neuropsychological syndromes in systemic lupus erythematosus

Table 2 Summary of the frequency of positive expression of antibodies to various ribosomal P protein components in cerebrospinal fluid^a

^aAntibodies to the C-terminal 22-amino acid sequence of ribosomal P protein (anti-P_C22), to highly purified ribosomal P proteins (anti-whole P), to the epitopes other than the C-terminal 22-amino acid sequence (anti-P_EX.C22), and to recombinant ribosomal P0 protein lacking the C-terminal 22-amino acid sequence (anti-C22-depleted rP0) in cerebrospinal fluid from patients with non-inflammatory neurological diseases (Control), with diffuse neuropsychiatric systemic lupus erythematosus (NP-SLE), or with focal NP-SLE were compared. ^bCutoff values were set as the mean + 3 standard deviations of the values in control group. Values in parenthesis mean (numbers of patients with positive results/total patient numbers) in each group.

ISSN: 1478-6362